News

Septerna, Inc. (Nasdaq: SEPN) and Novo Nordisk today announced an exclusive global collaboration and license agreement to discover, develop and commercialise oral small molecule medicines for obesity, type 2 diabetes and other cardiometabolic diseases.

This work is being made possible thanks to a landmark agreement between the cutting-edge biotech firm Bicycle Therapeutics, and the UK Nuclear Decommissioning Authority, being announced today (Tuesday 16 December). Bicycle was co-founded by one of the luminaries of British science, Sir Greg Winter, who was honoured with the Nobel Prize for Chemistry in 2018.

In March 2026, Nobel Laureate-founded Bicycle Therapeutics began enrolling patients in a Phase 2 clinical trial to evaluate efficacy, safety, and pharmacokinetics of nuzefatide in adult patients with recurrent PDAC, and the first patient was successfully dosed in April 2026.

We congraulate Dr. Frederick Jay Ramsdell, scientific co-founder, former Chief Scientific Officer, and current Scientific Advisory Board Chair of Sonoma Biotherapeutics, Inc., on being awarded the 2025 Nobel Prize in Physiology or Medicine for his groundbreaking contributions to regulatory T cell (Treg) biology and cell therapy.

Galera Therapeutics, Inc. (“Galera”) (OTC: GRTX), a clinical-stage biopharmaceutical company focused on advancing a pan-NOS inhibitor through clinical development for patients with the hardest-to-treat forms of advanced breast cancer, and Obsidian Therapeutics, Inc. (“Obsidian”), a privately-held clinical-stage biopharmaceutical company harnessing novel protein-regulation technology to develop engineered tumor infiltrating lymphocyte, (“TIL”), cell therapies, today announced that they have entered into a definitive merger agreement to combine in an all-stock transaction.

Allay Therapeutics, a clinical-stage biotechnology company pioneering ultra-sustained analgesic products to transform post-surgical pain management and recuperation, today announced the completion of a $57.5M Series D financing round with leading global investors.  Lightstone Ventures and ClavystBio co-led the Series D financing with participation by existing investors NEA, Arboretum Ventures, Vertex Growth, Vertex Ventures Healthcare, and Brandon Capital. New investors joining the round were IPD Capital, EDBI and SGInnovate, and HSBC Innovation Banking also provided additional venture debt financing to the Company. Allay also announced that Joe Zakrzewski, an experienced pharmaceutical executive, has been appointed Chairman of the Board of Directors, and Anselm Tan of ClavystBio will also join Allay’s board, associated with the financing.